69893

2-Morpholinoethyl isocyanide

≥98.0% (GC)

• 동의어(들): 4-(2-Isocyanoethyl)morpholine, MEI
• 실험식(Hill 표기법): C₇H₁₂N₂O
• CAS Number: 78375-48-1
• Molecular Weight: 140.18
• Beilstein: 4666990
• MDL number: MFCD00040506
• UNSPSC 코드: 12352100
• PubChem Substance ID: 57652222
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: ≥98.0% (GC)
• 형태: liquid
• refractive index: n20/D 1.469
• bp: 72-73 °C/0.7 mmHg (lit.)
• density: 1.017 g/mL at 20 °C (lit.)
• 작용기: amine; ether; isonitrile
• 저장 온도: −20°C
• SMILES string: [C-]#[N+]CCN1CCOCC1
• InChI: 1S/C7H12N2O/c1-8-2-3-9-4-6-10-7-5-9/h2-7H2
• InChI key: MFRZPLYKVDHOSN-UHFFFAOYSA-N

설명

애플리케이션

2-Morpholinoethyl isocyanide can be used for the synthesis of:

• Nitrogen acyclic carbene (NAC) complexes to be used as catalysts for the synthesis of phenol and hydration of alkynes.
• Variety of imidazo[1,2-a]pyridines and α-acylaminoamides by Ugi condensation reaction.
• 2-Aminobenzoxazoles and 3-aminobenzoxazines having important therapeutic activities.

It can also be used as a ligand in bis-cyclometalated iridium complexes for the organic light emitting diodes (OLEDs).

기타 정보

Potent coupling reagent for peptide synthesis giving higher yields and less racemization than DCCI; Reagent used in a Passerini-like reaction to alpha-hydroxy amides

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311 + H331,H315,H319,H335
• 예방조치 성명서: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): 230.0 °F - closed cup
• Flash Point (°C): 110 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter