64046
2,3-Dimercapto-1-propanol
≥98% (iodometric)
동의어(들):
BAL, British anti-Lewisite, DMP, Dimercaprol, Dithioglycerol
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
Linear Formula:
HOCH2CH(SH)CH2SH
CAS Number:
Molecular Weight:
124.23
Beilstein:
1732058
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
분석
≥98% (iodometric)
refractive index
n20/D 1.572-1.574
n20/D 1.573 (lit.)
bp
120 °C/15 mmHg (lit.)
density
1.239 g/mL at 25 °C (lit.)
작용기
hydroxyl
thiol
저장 온도
2-8°C
SMILES string
OCC(S)CS
InChI
1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2
InChI key
WQABCVAJNWAXTE-UHFFFAOYSA-N
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일반 설명
Dimercapto-1-propanol acts as a chelating agent and forms stable complexes with certain heavy metals, including arsenic, mercury, and lead.
애플리케이션
2,3-Dimercapto-1-propanol has been used in synthesizing novel (2-substituted phenyl-1,3-dithiolan-4-yl) methanol (PDTM) derivatives, which are potent tyrosinase inhibitors. It can also be considered for developing new drugs against AIDS due to its ability to inhibit HIV-1 tat activity.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
233.6 °F - closed cup
Flash Point (°C)
112 °C - closed cup
개인 보호 장비
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
이미 열람한 고객
S Kubota et al.
AIDS research and human retroviruses, 6(7), 919-927 (1990-07-01)
We have examined the effect of 2,3 dimercapto-1-propanol (DMP), which is known as an anti-heavy metal-poisoning drug, against human immunodeficiency virus type 1 (HIV-1). We demonstrate that DMP inhibited transactivation directed by tat protein, which is a metal containing transcriptional
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Do Hyun Kim et al.
Drug design, development and therapy, 11, 827-836 (2017-03-30)
The authors designed and synthesized 17 (2-substituted phenyl-1,3-dithiolan-4-yl) methanol (PDTM) derivatives to find a new chemical scaffold, showing excellent tyrosinase-inhibitory activity. Their tyrosinase-inhibitory activities were evaluated against mushroom tyrosinase at 50 μM, and five of the PDTM derivatives (PDTM3, PDTM7-PDTM9
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