607851
L-Glutamic acid-13C5,15N
98 atom % 15N, 98 atom % 13C, 95% (CP)
동의어(들):
(S)-2-Aminopentanedioic acid-13C5,15N, 13C and 15N Labeled L-glutamic acid, Glu-13C5,15N
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모든 사진(1)
About This Item
Linear Formula:
HO213C(13CH2)213CH(15NH2)13CO2H
CAS Number:
Molecular Weight:
153.09
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.12
추천 제품
동위원소 순도
98 atom % 13C
98 atom % 15N
분석
95% (CP)
양식
solid
광학 활성
[α]25/D +31.0°, c = 2 in 5 M HCl
기술
bio NMR: suitable
mp
205 °C (dec.) (lit.)
질량 이동
M+6
SMILES string
[15NH2][13C@@H]([13CH2][13CH2][13C](O)=O)[13C](O)=O
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1
InChI key
WHUUTDBJXJRKMK-UFLWJPECSA-N
일반 설명
Glutamic acid is an amino acid with an acidic side group. It works as a proton donor. Decarboxylation of glutamic acid results in the formation of GABA (γ aminobutyric acid), a potent neurotransmitter. Isotope labeled amino acids are required for the production of isotopically labeled proteins.
포장
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Fumihiro Eto et al.
Scientific reports, 10(1), 7435-7435 (2020-05-06)
The brain consists of various areas with anatomical features. Neurons communicate with one another via excitatory or inhibitory synaptic transmission. Altered abundance of neurotransmitters, including glutamate and gamma-aminobutyric acid (GABA), in specific brain regions is closely involved in severe neurological
Kishore K Mahalingan et al.
Nature structural & molecular biology, 27(9), 802-813 (2020-08-05)
Glutamylation, introduced by tubulin tyrosine ligase-like (TTLL) enzymes, is the most abundant modification of brain tubulin. Essential effector proteins read the tubulin glutamylation pattern, and its misregulation causes neurodegeneration. TTLL glutamylases post-translationally add glutamates to internal glutamates in tubulin carboxy-terminal
Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)
Isotope labeling for solution and solid-state NMR spectroscopy of membrane proteins.
Verardi R, et al.
Advances in Experimental Medicine and Biology, 992, 35-62 (2012)
Incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver in a cell-free system.
SIMKIN JL and WORK TS
The Biochemical Journal, 67, 617-624 (1957)
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