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Merck
모든 사진(1)

Key Documents

607983

Sigma-Aldrich

L-Glutamine-13C5,15N2

98 atom % 13C, 98 atom % 15N

동의어(들):

(S)-2,5-Diamino-5-oxopentanoic acid-13C5-15N2, L-Glutamic acid 5-amide-13C5-15N2, L-Glutamine-ul-13C,15N, 13C and 15N Labeled glutamine

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About This Item

Linear Formula:
H215N13CO(13CH2)213CH(15NH2)13CO2H
Molecular Weight:
153.09
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.12

동위원소 순도

98 atom % 13C
98 atom % 15N

분석

95% (CP)

형태

solid

광학 활성

[α]25/D +33.0°, c = 2 in 5 M HCl

기술

bio NMR: suitable

mp

185 °C (dec.) (lit.)

질량 이동

M+7

SMILES string

[15NH2][13C@@H]([13CH2][13CH2][13C]([15NH2])=O)[13C](O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1

InChI key

ZDXPYRJPNDTMRX-YIDSDQPMSA-N

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일반 설명

Glutamine is an amino acid with an uncharged polar side chain. It can be catabolized to glutamate and ammonia. Glutamine is the most abundant amino acid in the central nervous system. Isotope labeled amino acids are required for the production of isotopically labeled proteins.

포장

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Stable Isotope Resolved Metabolomics Studies in Ex Vivo TIssue Slices.
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Bio-protocol, 6, e1730-e1730 (2016)
13C Tracer Studies of Metabolism in Mouse Tumor Xenografts.
Lane AN, et al.
Bio-protocol, 5, bio-protocol (2015)
Wei Yan et al.
Nature cell biology, 20(5), 597-609 (2018-04-18)
Cancer and other cells residing in the same niche engage various modes of interactions to synchronize and buffer the negative effects of environmental changes. Extracellular microRNAs (miRNAs) have recently been implicated in the intercellular crosstalk. Here we show a mechanistic
Manabu Kodama et al.
Nature communications, 11(1), 1320-1320 (2020-03-19)
Glucose metabolism is remodeled in cancer, but the global pattern of cancer-specific metabolic changes remains unclear. Here we show, using the comprehensive measurement of metabolic enzymes by large-scale targeted proteomics, that the metabolism both carbon and nitrogen is altered during
Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)

관련 콘텐츠

Protein structure provides valuable information that can be used to infer protein function. The study of protein structure and mapping of protein interactions, expression levels, and location enables the identification of disease biomarkers and potential drug targets for therapeutic treatment.

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