536822

PAMAM-OH dendrimer, generation 6 solution

5 wt. % in methanol

• Linear Formula: [NH₂(CH₂)₂NH₂]:(G=6);dendri PAMAM(NHCH₂CH₂OH)₂₅₆
• Molecular Weight: 58298.21
• MDL number: MFCD00197936
• UNSPSC 코드: 12162002
• NACRES: NA.25

속성

• 설명: amidoethanol surface groups
• 형태: liquid
• 분자량: generation 6
• 특징: core type ethylenediamine core (2-carbon core)
• 농도: 5 wt. % in methanol
• 표면기 개수: 256
• refractive index: n20/D 1.336
• density: 0.807 g/mL at 25 °C
• 저장 온도: 2-8°C

설명

일반 설명

PAMAM-OH (poly(amidoamine) dendrimers are highly branched core-shell nanostructures with surface hydroxyl groups. The presence of hydroxyl groups on the surface of the PAMAM-OH dendrimer molecule leads to stronger interaction with the components of the cell membrane via the formation of hydrogen bonds. This type of interaction can modify the properties and function of cell membranes. PAMAM-OH dendrimers also have an advantage over PAMAM dendrimers in terms of cytotoxicity and aggregation problems because of the absence of amine functionality.

애플리케이션

PAMAM-OH dendrimer can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers.

물리적 형태

Contains 256 surface hydroxyl groups.

법적 정보

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 51.8 °F - closed cup
• Flash Point (°C): 11 °C - closed cup