531413

2,2-Difluoro-2-(fluorosulfonyl)acetic acid

97%

• 동의어(들): (Fluorosulfonyl)difluoroacetic acid
• Linear Formula: FSO₂CF₂CO₂H
• CAS Number: 1717-59-5
• Molecular Weight: 178.09
• MDL number: MFCD01320807
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24877815
• NACRES: NA.22

속성

• 분석: 97%
• 반응 적합성: reaction type: click chemistry
• refractive index: n20/D 1.36 (lit.)
• bp: 153 °C (lit.)
• density: 1.723 g/mL at 25 °C (lit.)
• 작용기: carboxylic acid; fluoro
• SMILES string: OC(=O)C(F)(F)S(F)(=O)=O
• InChI: 1S/C2HF3O4S/c3-2(4,1(6)7)10(5,8)9/h(H,6,7)
• InChI key: VYDQUABHDFWIIX-UHFFFAOYSA-N

설명

일반 설명

2,2-Difluoro-2-(fluorosulfonyl)acetic acid reagent is employed as a difluorocarbene source for difluoromethylation of phenolic hydroxyl groups.

애플리케이션

2,2-Difluoro-2-(fluorosulfonyl)acetic acid may be used in the following processes:

• Preparation of 1-difluoromethyl-2-oxo-1,2-dihydropyridine analogs by reacting with the corresponding 2-chloropyridines.
• Prepration of silyl fluorosulfonyldifluoroacetate as new highly efficient difluorocarbene reagent for cyclopropanation of alkenes.
• Regio- and stereoselective free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides.

안전성 정보

• 픽토그램: GHS06,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310,H314
• 예방조치 성명서: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P361 + P364 - P405
• Hazard Classifications: Acute Tox. 2 Oral - Skin Corr. 1A
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): 230.0 °F - closed cup
• Flash Point (°C): 110 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges