42085

1-Fluoro-2,4-dinitrobenzene

purum p.a., ≥98.0% (GC)

• 동의어(들): 2,4-Dinitro-1-fluorobenzene, DNFB, DNPF, FDNB, Sanger reagent
• Linear Formula: (O₂N)₂C₆H₃F
• CAS Number: 70-34-8
• Molecular Weight: 186.10
• Beilstein: 398632
• EC Number: 200-734-3
• MDL number: MFCD00007056
• UNSPSC 코드: 12352100
• PubChem Substance ID: 57650098
• NACRES: NA.22

속성

• grade: purum p.a.
• Quality Level: 100
• 분석: ≥98.0% (GC)
• 양식: liquid
• refractive index: n20/D 1.569 (lit.)
• bp: 178 °C/25 mmHg (lit.)
• mp: 25-27 °C (lit.)
• density: 1.482 g/mL at 25 °C (lit.)
• 양이온 미량물: Ca: ≤50 mg/kg; Cd: ≤50 mg/kg; Co: ≤50 mg/kg; Cu: ≤50 mg/kg; Fe: ≤50 mg/kg; K: ≤100 mg/kg; Na: ≤100 mg/kg; Ni: ≤50 mg/kg; Pb: ≤50 mg/kg; Zn: ≤50 mg/kg
• 작용기: fluoro; nitro
• 저장 온도: 2-8°C
• SMILES string: [O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O
• InChI: 1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H
• InChI key: LOTKRQAVGJMPNV-UHFFFAOYSA-N

설명

일반 설명

1-Fluoro-2,4-dinitrobenzene(FDNB, Sanger′s reagent) is used to identify the amino acid sequence. Thischemical is used to label the free amino groups in proteins and peptides. Itcan also be used to protect the amine group, and for phenol deoxygenation. Additionally,it is a very helpful reagent for nucleophilic substitution reactions tointroduce a chromophore group to amines, phenols, and thiols.

애플리케이션

1-Fluoro-2,4-dinitrobenzene is used as a derivatization agent:

• For aminoglycoside compounds such as amikacine, tobramycine, gentamycine, sisomycine, neamine, neomycine-B and neomycine-C.

1-Fluoro-2,4-dinitrobenzene can also be used:

• To examine the kinetic analysis and analytical uses of reaction with thiols in the presence of several surfactants.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H317,H319,H335,H373
• 예방조치 성명서: P260 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 327.2 °F
• Flash Point (°C): 164 °C
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves