추천 제품
동위원소 순도
98 atom % 13C
Quality Level
분석
99% (CP)
mp
>300 °C (lit.)
질량 이동
M+1
SMILES string
[Na].O[13C](O)=O
InChI
1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1/i1+1;
InChI key
UIIMBOGNXHQVGW-YTBWXGASSA-M
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일반 설명
Sodium hydrogencarbonate-13C is isotopically enriched compound of sodium bicarbonate.
애플리케이션
Sodium bicarbonate-13C can be used:
- As a probe for NMR− and MRI− based pH imaging.
- To predict the reaction mechanism in selective hydrogenation of bicarbonate to formate, catalyzed by a ruthenium(III) complex.
- For 13C labeling of amino acid sample for compound-specific stable isotope analysis (CSIA).
Sodium bicarbonate-13C is used to study the lactate metabolism by using hyperpolarized 13C pH imaging and multiparametric MRI.This reagent can be used as probe in nuclear magnetic resonance spectroscopy studies, which enabled large signal gains for low-toxicity hyperpolarized 13C pH imaging in a phantom and in vivo in a murine model of prostate cancer.
포장
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Current concepts on hyperpolarized molecules in MRI.
Current Opinion in Chemical Biology, 14(1), 90-96 (2010)
Quantified pH imaging with hyperpolarized 13 C-bicarbonate
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 73(6), 2274-2282 (2015)
NMR in biomedicine, 24(8), 1006-1015 (2011-08-04)
pH is a fundamental physiological parameter that is tightly controlled by endogenous buffers. The acid-base balance is altered in many disease states, such as inflammation, ischemia and cancer. Despite the importance of pH, there are currently no routine methods for
Magnetic resonance imaging of pH in vivo using hyperpolarized 13 C-labelled bicarbonate.
Nature, 453(7197), 940-940 (2008)
RuIII (edta) catalyzed hydrogenation of bicarbonate to formate.
Journal of Coordination Chemistry, 69(4), 650-655 (2016)
문서
We present an article about the hyperpolarization of 13C labeled metabolites, especially pyruvic acid, using dynamic nuclear polarization (DNP) that allows real-time magnetic resonance spectroscopy.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.