345350

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine

• 동의어(들): (1S)-(+)-(Camphorylsulfonyl)oxaziridine, (1S)-(+)-2,N-Epoxy-exo-10,2-bornanesultam
• 실험식(Hill 표기법): C₁₀H₁₅NO₃S
• CAS Number: 104322-63-6
• Molecular Weight: 229.30
• Beilstein: 6274370
• MDL number: MFCD21332910
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24861312
• NACRES: NA.22

속성

• 형태: solid
• 광학 활성: [α]28/D +45°, c = 2 in chloroform
• 불순물: <1% toluene
• mp: 172-174 °C (lit.)
• 저장 온도: 2-8°C
• SMILES string: CC1(C)[C@@H]2CC[C@]13CS(=O)(=O)N4O[C@@]34C2
• InChI: 1S/C10H15NO3S/c1-8(2)7-3-4-9(8)6-15(12,13)11-10(9,5-7)14-11/h7H,3-6H2,1-2H3/t7-,9+,10+,11?/m1/s1
• InChI key: GBBJBUGPGFNISJ-YDQXZVTASA-N

설명

애플리케이션

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine can be used:

• To convert prochiral ketone enolates into optically active α-hydroxy ketones via enantioselective asymmetric oxidation.
• In the synthesis of thymidine oligonucleotides connected through pyrophosphates.
• In the asymmetric synthesis of proton pump inhibitors like (R)-Rabeprazole sodium and (R)-Lansoprazole sodium from the corresponding DBU salt of prochiral sulfide.
• In the preparation of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides by oxidizing the corresponding phosphinoacetate.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)