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Merck
모든 사진(1)

주요 문서

335665

Sigma-Aldrich

7-Hydroxycoumarinyl-4-acetic acid

97%

동의어(들):

Umbelliferone-4-acetic acid

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About This Item

실험식(Hill 표기법):
C11H8O5
CAS Number:
Molecular Weight:
220.18
Beilstein:
204777
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

양식

powder

mp

212 °C (dec.) (lit.)

작용기

carboxylic acid
ester

SMILES string

OC(=O)CC1=CC(=O)Oc2cc(O)ccc12

InChI

1S/C11H8O5/c12-7-1-2-8-6(3-10(13)14)4-11(15)16-9(8)5-7/h1-2,4-5,12H,3H2,(H,13,14)

InChI key

BNHPMQBVNXMPDU-UHFFFAOYSA-N

애플리케이션

7-Hydroxycoumarinyl-4-acetic acid was used in the synthesis of novel and specific enzyme substrates for Maroteaux-Lamy (MPS VI) and Morquio A (MPS IVA) diseases. It was also employed as ionic liquid matrice for MALDI-TOF MS of proteins, peptides and carbohydrates.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

이미 열람한 고객

E J Demant et al.
Analytical biochemistry, 295(1), 38-44 (2001-07-31)
The fluorescence-based long-chain fatty acid probe BSA-HCA (bovine serum albumin labeled with 7-hydroxycoumarin-4-acetic acid) is shown to respond to binding of long-chain acyl-CoA thioesters by quenching of the 450 nm fluorescence emission. As determined by spectrofluorometric titration, binding affinities for
E J Demant
Analytical biochemistry, 267(2), 366-372 (1999-02-26)
A covalent complex between bovine serum albumin and 7-hydroxycoumarin-4-acetic acid (BSA-HCA) shows a strong fluorescence band at lambdamax = 450 nm upon excitation at 375 nm. Quenching of the fluorescence emission accompanies the association of fatty acids (FA) to BSA-HCA
Trisha A Duffey et al.
Bioorganic & medicinal chemistry letters, 20(20), 5994-5996 (2010-09-14)
In continued efforts to develop enzymatic assays for lysosomal storage diseases appropriate for newborn screening laboratories we have synthesized novel and specific enzyme substrates for Maroteaux-Lamy (MPS VI) and Morquio A (MPS IVA) diseases. The sulfated monosaccharide derivatives were found
Erland J F Demant et al.
The Biochemical journal, 363(Pt 3), 809-815 (2002-04-20)
The kinetics of the interaction of long-chain fatty acids (referred to as fatty acids) with albumin is critical to understanding the role of albumin in fatty acid transport. In this study we have determined the kinetics of fatty acid dissociation
Yan Chen et al.
Analytical biochemistry, 540-541, 38-44 (2017-11-13)
To establish a high throughput, low cost, and simple nanotechnology-based method for the detection of single nucleotide polymorphism (SNP) loci in type 2 diabetes mellitus (T2DM). Multiplex ligase detection reaction (LDR) amplification was performed using fluorescently labeled magnetic nanosphere-bound upstream

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