331376

Phenylmagnesium bromide solution

1.0 M in THF

• 동의어(들): PhMgBr solution
• Linear Formula: C₆H₅MgBr
• CAS Number: 100-58-3
• Molecular Weight: 181.31
• Beilstein: 3588849
• MDL number: MFCD00000038
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24859956
• NACRES: NA.22

속성

• Quality Level: 200
• 반응 적합성: reaction type: Grignard Reaction
• 농도: 1.0 M in THF
• density: 1.004 g/mL at 25 °C
• SMILES string: Br[Mg]c1ccccc1
• InChI: 1S/C6H5.BrH.Mg/c1-2-4-6-5-3-1;;/h1-5H;1H;/q;;+1/p-1
• InChI key: ANRQGKOBLBYXFM-UHFFFAOYSA-M

설명

애플리케이션

Phenylmagnesium bromide (PhMgBr) solution is an organomagnesium reagent mainly used in Grignard reaction, which finds application as the key step in the synthesis of (S)-2(diphenylmethyl)pyrrolidine, a chiral solvating agent for the NMR analysis. PhMgBr can also undergo palladium-catalyzed Grignard coupling with alkyl chlorides to form the cross-coupled product in good yield.

기타 정보

Storage below 25°C may cause crystallization. Warm gently to redissolve solid.

안전성 정보

• 픽토그램: GHS02,GHS08,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H314,H335,H336,H351
• 예방조치 성명서: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• 표적 기관: Respiratory system
• 보충제 위험성: EUH014,EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 1.4 °F - closed cup
• Flash Point (°C): -17 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter