324671

Potassium bis(trimethylsilyl)amide

95%

• 동의어(들): Hexamethyldisilazane potassium salt, Potassium hexamethyldisilazide
• Linear Formula: [(CH₃)₃Si]₂NK
• CAS Number: 40949-94-8
• Molecular Weight: 199.48
• Beilstein: 4006754
• MDL number: MFCD00010330
• UNSPSC 코드: 12352111
• PubChem Substance ID: 24859460
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 95%
• 양식: solid
• density: 0.877 g/cm³ at 20 °C
• SMILES string: C[Si](C)(C)N([K])[Si](C)(C)C
• InChI: 1S/C6H18NSi2.K/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
• InChI key: IUBQJLUDMLPAGT-UHFFFAOYSA-N

설명

일반 설명

Potassium bis(trimethylsilyl)amide is commonly abbreviated as KHMDS with molecular formula [(CH₃)₃Si]₂NK. It is widely used as Bronsted base in synthesis.

KHMDS is a base catalyst, that shows high activity and selectivity for the alkylation of alkylpyridines.

애플리케이션

Anionic initiator used in the preparation of poly(ethylene oxide). Sterically hindered base employed in selective cyclization reactions. Also used in the preparation of lanthanide complexes.

특징 및 장점

Potassium bis(trimethylsilyl)amide (KHMDS):

• Easily available.
• Good selectivity for the benzylic C−H bonds.
• Good reactivity for sterically crowded C−H bonds.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• 보충제 위험성: EUH014
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges