์ถ์ฒ ์ ํ
Quality Level
๋ถ์
97%
refractive index
n20/D 1.592 (lit.)
bp
90-92 ยฐC (lit.)
density
1.102 g/mL at 25 ยฐC (lit.)
SMILES string
Nc1cccc2CCCc12
InChI
1S/C9H11N/c10-9-6-2-4-7-3-1-5-8(7)9/h2,4,6H,1,3,5,10H2
InChI key
RXTJLDXSGNEJIT-UHFFFAOYSA-N
์ผ๋ฐ ์ค๋ช
4-Aminoindan undergoes nucleophlic addition reaction with 2-chloroacetylisocyanate to yield 1-(2-chloroacetyl)-3-(2,3-dihydro-1H-inden-4-yl)-urea.
์ ํ๋ฆฌ์ผ์ด์
4-Aminoindan was used in the synthesis of 4,5-dihydro-N-(2,3-dihydro-1H-inden-4-yl)oxazol-2-amine and 1-(2-chloroethyl)-3-(2,3-dihydro-1H-inden-4-yl)urea.
์ ํธ์ด
Warning
์ ํด ๋ฐ ์ํ ์ฑ๋ช ์
์๋ฐฉ์กฐ์น ์ฑ๋ช ์
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
ํ์ ๊ธฐ๊ด
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (ยฐF)
Not applicable
Flash Point (ยฐC)
Not applicable
๊ฐ์ธ ๋ณดํธ ์ฅ๋น
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
๊ฐ์ฅ ์ต์ ๋ฒ์ ์ค ํ๋๋ฅผ ์ ํํ์ธ์:
์ด ์ ํ์ ์ด๋ฏธ ๊ฐ์ง๊ณ ๊ณ์ญ๋๊น?
๋ฌธ์ ๋ผ์ด๋ธ๋ฌ๋ฆฌ์์ ์ต๊ทผ์ ๊ตฌ๋งคํ ์ ํ์ ๋ํ ๋ฌธ์๋ฅผ ์ฐพ์๋ณด์ธ์.
Bioorganic & medicinal chemistry, 15(13), 4456-4469 (2007-05-15)
A number of N-phenyl-N'-(2-chloroethyl)ureas (CEUs) have been shown to be potent antimitotics through their covalent binding to the colchicine-binding site on intracellular beta-tubulin. The present communication aimed to evaluate the role of the electrophilic 2-chloroethyl amino moiety of CEU on
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