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Merck
모든 사진(1)

주요 문서

159425

Sigma-Aldrich

9-Chloroacridine

97%

동의어(들):

9-Chloroacridine

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About This Item

실험식(Hill 표기법):
C13H8ClN
CAS Number:
Molecular Weight:
213.66
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

양식

solid

mp

116-120 °C (lit.)

작용기

chloro

SMILES string

Clc1c2ccccc2nc3ccccc13

InChI

1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H

InChI key

BPXINCHFOLVVSG-UHFFFAOYSA-N

애플리케이션

9-Chloroacridine was employed as chromogenic reagent in the spectrophotometric method for the quantitative determination of dapsone. It was also used in the synthesis of:
  • series of novel chalcones bearing acridine moiety attached to the amino group in their ring A
  • new acridine derivatives
  • 9-phenoxyacridine and 4-phenoxyfuro[2,3-b]quinoline derivatives

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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Slide 1 of 2

1 of 2

Paula Bosch et al.
Materials (Basel, Switzerland), 12(18) (2019-09-22)
A second-generation poly(propylene imine) dendrimer modified with acridine and its Cu(II) complex have been synthesized for the first time. It has been found that two copper ions form complexes with the nitrogen atoms of the dendrimeric core by coordinate bonds.
Yeh-Long Chen et al.
Bioorganic & medicinal chemistry, 11(18), 3921-3927 (2003-08-21)
Mast cells, neutrophils and macrophages are important inflammatory cells that have been implicated in the pathogenesis of acute and chronic inflammatory diseases. To explore a novel anti-inflammatory agent, we have synthesized certain 9-phenoxyacridine and 4-phenoxyfuro[2,3-b]quinoline derivatives and evaluated their anti-inflammatory
Arumugasamy Elangovan et al.
Organic & biomolecular chemistry, 2(21), 3113-3118 (2004-10-27)
Electrogenerated chemiluminescence (ECL) of six new ethyne-based acridine derivatives (1-6) has been studied. The new acridine derivatives were synthesized by cross-coupling of 9-chloroacridine and corresponding donor-substituted phenylethynes under modified Sonogashira conditions. The donor groups were varied in the order of
V Tomar et al.
European journal of medicinal chemistry, 45(2), 745-751 (2009-12-22)
A series of novel chalcones bearing acridine moiety attached to the amino group in their ring A have been synthesized through noncatalyzed nucleophilic aromatic substitution reaction between various 3'-aminochalcone or 4'-aminochalcones and 9-chloroacridine. The synthesized chalcone derivatives have been characterized
I Shoukrallah et al.
Die Pharmazie, 45(9), 675-677 (1990-09-01)
A spectrophotometric method for the quantitative determination of dapsone (1) has been developed through a condensation reaction of 9-chloroacridine as a chromogen and the amino groups of 1. The reaction variables were investigated and optimized. The resultant colored products is

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