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Merck
모든 사진(1)

주요 문서

15500

Sigma-Aldrich

Boc-Ser-OH

≥99.0% (T), for peptide synthesis

동의어(들):

N-(tert-Butoxycarbonyl)-L-serine, Boc-L-serine

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About This Item

Linear Formula:
HOCH2CH(COOH)NHCOOC(CH3)3
CAS Number:
Molecular Weight:
205.21
Beilstein:
2212252
EC Number:
MDL number:
UNSPSC 코드:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

product name

Boc-Ser-OH, ≥99.0% (T)

Quality Level

분석

≥99.0% (T)

광학 활성

[α]20/D −3.5±0.5°, c = 2% in acetic acid

반응 적합성

reaction type: Boc solid-phase peptide synthesis

mp

91 °C (dec.) (lit.)

응용 분야

peptide synthesis

저장 온도

2-8°C

SMILES string

CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O

InChI

1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1

InChI key

FHOAKXBXYSJBGX-YFKPBYRVSA-N

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일반 설명

Boc-Ser-OH is an amino acid derivative.

애플리케이션

Boc-Ser-OH may be used in the synthesis of the following:
  • 2-(N-Fmoc)-3-(N-Boc-N-methoxy)-diaminopropanoic acid (Fmoc: 9-fluorenylmethoxycarbonyl; Boc: t-butyloxycarbonyl)
  • Boc-Ser-Leu-OMe
  • cyclic peptide synthesis
  • benzylsulfonyl-D-Ser-Ser-4-amidinobenzylamide
Building block in peptide synthesis. Starting material for the synthesis of various α-amino acids via the β-lactone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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이미 열람한 고객

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Synthesis of cyclic peptides via O-N-acyl migration.
Lecaillon J, et al.
Tetrahedron Letters, 49(31), 4674-4676 (2008)
The relationship between taste and primary structure of ?delicious peptide?(Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala) from beef soup.
Tamura M, et al.
Agricultural and Biological Chemistry, 53(2), 319-325 (1989)
Michael R Carrasco et al.
Biopolymers, 84(4), 414-420 (2006-03-02)
Amino acids with N-alkylaminooxy side chains have proven effective for the rapid synthesis of neoglycopeptides. Chemoselective reaction of reducing sugars with peptides containing these amino acids provides glycoconjugates that are structurally similar to their natural counterparts. 2-(N-Fmoc)-3-(N-Boc-N-methoxy)-diaminopropanoic acid (Fmoc: 9-fluorenylmethoxycarbonyl;
O García-Suárez et al.
Immunology, 94(2), 235-241 (1998-09-19)
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Development (Cambridge, England), 148(18) (2021-08-10)
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