추천 제품
Quality Level
분석
97%
mp
172-174 °C (lit.)
작용기
nitrile
SMILES string
Nc1n[nH]cc1C#N
InChI
1S/C4H4N4/c5-1-3-2-7-8-4(3)6/h2H,(H3,6,7,8)
InChI key
FFNKBQRKZRMYCL-UHFFFAOYSA-N
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관련 카테고리
애플리케이션
3-amino-4-cyanopyrazole was used to study the impurities in zaleplon bulk drug.
Building block used in the synthesis of a variety of heterocycles.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Synlett, 65-65 (2006)
Journal of pharmaceutical and biomedical analysis, 44(1), 101-109 (2007-03-21)
Zaleplon is a pyrazolopyrimidine derivative and possesses sedative and hypnotic properties. Seven unknown impurities in zaleplon bulk drug at levels below 0.1% were detected by reverse-phase high performance liquid chromatography (HPLC). The starting material, 3-amino-4-cyanopyrazole and an intermediate, N-[3-[3-(dimethylamino)-1-oxo-2-propenyl]-phenyl]-N-ethylacetamide (DOPEA)
Helvetica Chimica Acta, 89, 30-30 (2006)
Molecular and cellular endocrinology, 393(1-2), 56-64 (2014-06-17)
CLM29 (a pyrazolo[3,4-d]pyrimidine, that inhibits RET, epidermal growth factor receptor, vascular endothelial growth factor receptor, and has an anti-angiogenic activity) has anti-neoplastic activity in papillary dedifferentiated thyroid cancer. Here we tested CLM29 in medullary thyroid cancer (MTC), in primary MTC
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