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Merck

GRIN2C

glutamate receptor, ionotropic, N-methyl D-aspartate 2C

동의어:
GluN2C, NMDAR2C, NR2C
:
UniProtKB ID:
Clone ID:
  • Human(2905) Summary: This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • Mouse(14813) glutamate receptor, ionotropic, NMDA2C (epsilon 3)
  • Rat(24411) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • sheep(101102915) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • domestic guinea pig(100721967) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • naked mole-rat(101698922) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • chicken(431090) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • dog(483302) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • cow(535158) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • domestic cat(101091740) glutamate receptor, ionotropic, N-methyl D-aspartate 2C

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Small Molecule - Agonist

제품 번호
설명
L-Tyrosine hydrochloride, ≥98% (TLC),
mouse, rat, human
D-Cycloserine, synthetic,
human
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
human, rat
D-Cycloserine, ,
human, mouse, rat
N-Acetyl-Asp-Glu, ≥97% (TLC),
mouse, human, rat

Small Molecule - Allosteric Modulator

제품 번호
설명
Acamprosate calcium, ≥98% (HPLC), powder,
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
human

Small Molecule - Antagonist

제품 번호
설명
Arcaine sulfate salt, ,
human
D(−)-2-Amino-5-phosphonopentanoic acid, NMDA receptor antagonist,
mouse, rat
Ifenprodil (+)-tartrate salt, ,
human
(±)-2-Amino-4-phosphonobutyric acid, solid,
rat, human
Felbamate, ,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B, Chemicon®, from rabbit,
종별 반응성
rat
응용분야
immunoprecipitation (IP)
western blot
Anti-GRIN2C antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-Glutamate Receptor NMDAR2C (NR2C) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Blocker

제품 번호
설명
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
human
Agmatine sulfate salt, ≥97%, powder,
human
Orphenadrine hydrochloride, ≥98.0% (AT),
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
human

Small Molecule - Inhibitor

제품 번호
설명
Pentamidine isethionate salt, powder,
human
Orphenadrine hydrochloride, ≥98.0% (AT),
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human GRIN2C,
human