추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
lyophilized powder
분자량
antigen 140 kDa (NR2C subunit)
antigen 180 kDa (NR2A and NR2B bands)
종 반응성
rat, human, mouse
기술
immunohistochemistry (frozen sections): 1:1000
immunoprecipitation (IP): 3 μL using 200 μg of rat cerebellum.
indirect immunofluorescence: 1:1000 using frozen sections
western blot: 1:1000 using 200 μg cell lysate
UniProt 수납 번호
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... GRIN2C(2905)
mouse ... Grin2c(14813)
rat ... Grin2c(24411)
면역원
N-terminal portion of NR2C (amino acids 25-130)
물리적 형태
Lyophilized from ammonium bicarbonate (5 mM).
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Luke A Esposito
Methods in molecular biology (Clifton, N.J.), 670, 71-84 (2010-10-23)
The accumulation of the amyloid-β (Aβ) peptide in the form of insoluble fibrillar deposits and soluble oligomeric aggregates is widely believed to play a causal role in Alzheimer's disease (AD). Proteolytic cleavage of APP by the β-site APP cleaving enzyme
Michele Buddle et al.
Brain research, 978(1-2), 38-50 (2003-07-02)
MAP2 (microtubule-associated protein 2) is a cytoskeletal phosphoprotein that regulates the dynamic assembly characteristics of microtubules and appears to provide scaffolding for organelle distribution into the dendrites and for the localization of signal transduction apparatus in dendrites, particularly near spines.
Stéphane Peineau et al.
Methods in molecular biology (Clifton, N.J.), 1677, 253-263 (2017-10-08)
Proving endogenous GluN presence and functions in microglia require complementary steps to demonstrate (1) that GluN genes are transcripted and translated, (2) their cellular localization, (3) that the GluN are functional, and (4) the role of the functional GluN. The
K K Yung
Neuroreport, 9(7), 1639-1644 (1998-06-19)
Immunocytochemical localization of metabotropic glutamate receptors (mGluRs) and ionotropic glutamate receptors (NMDA-type: NMDAR1 and NMDAR2A-C; AMPA-type: GluR1-4) was performed on sections of rat dorsal horn. Immunoreactivity for mGluR1 alpha was detected in laminae I-III of the dorsal horn, whilst mGluR2/3
H Monyer et al.
Science (New York, N.Y.), 256(5060), 1217-1221 (1992-05-22)
The N-methyl D-aspartate (NMDA) receptor subtype of glutamate-gated ion channels possesses high calcium permeability and unique voltage-dependent sensitivity to magnesium and is modulated by glycine. Molecular cloning identified three complementary DNA species of rat brain, encoding NMDA receptor subunits NMDAR2A
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