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Merck
  • Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans.

Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans.

Antimicrobial agents and chemotherapy (2008-09-17)
Nathan P Wiederhold, Jodi L Grabinski, Guillermo Garcia-Effron, David S Perlin, Samuel A Lee
要旨

Pyrosequencing was compared to Sanger dideoxy sequencing to detect mutations in FKS1 responsible for reduced echinocandin susceptibility in Candida albicans. These methods were in complete agreement for 10 of 12 clinical isolates with elevated echinocandin MICs, supporting the potential feasibility of pyrosequencing to detect mutations within diploid fungi.

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Sigma-Aldrich
ヒト血清, from human male AB plasma, USA origin, sterile-filtered
Sigma-Aldrich
ヒト血清, Heat Inactivated, from human male AB plasma, USA origin, sterile-filtered
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ヒト血清, (from male AB clotted whole blood), USA origin, sterile-filtered
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ヒト血清, Heat Inactivated (from male AB clotted whole blood), USA origin, sterile-filtered
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