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Merck

V900418

Sigma-Aldrich

ビオチン

Vetec, reagent grade, ≥99%

別名:

D-ビオチン, Bios II, ビタミンB7, ビタミンH, 補酵素A

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About This Item

実験式(ヒル表記法):
C10H16N2O3S
CAS番号:
分子量:
244.31
Beilstein:
86838
EC Number:
MDL番号:
UNSPSCコード:
12352201
PubChem Substance ID:

グレード

reagent grade

製品種目

Vetec

アッセイ

≥99%

形状

powder

white to off-white

mp

231-233 °C (lit.)

保管温度

2-8°C

SMILES記法

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI Key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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詳細

Biotin (vitamin B7 or vitamin H) is a water-soluble B complex vitamin, which consists of an uredo ring fused by a tetrahydrothiophene ring. It is available in various foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. Biotin is also produced by the normal gut flora.

生物化学的/生理学的作用

Biotin is a vital cofactor for carboxylase enzymes in several metabolic pathways. It also functions as a coenzyme in the metabolism of fatty acids, isoleucine and valine. Biotin assists the transfer of carbon dioxide and also sustains a steady blood sugar level. Biotin is implicated in gluconeogenesis and citric acid cycle. It is involved in keratin synthesis and hence is used as a supplement for skin, hair and nail growth. Biotin is required for cell growth, production of fatty acids and the metabolism of fats and amino acids.

法的情報

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

11 - Combustible Solids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

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Slide 1 of 2

1 of 2

Vitamin H and their role in ruminant: A Review
Pour HA, et al.
Annals of Biological Research, 3(4), 1929-1933 (2012)
A Review of the Use of Biotin for Hair Loss
Patel DP, et al.
Skin Appendage Disorder, 3(3), 166-166 (2017)
John J Tukker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(16), 6809-6825 (2013-04-19)
Hippocampal CA3 area generates temporally structured network activity such as sharp waves and gamma and theta oscillations. Parvalbumin-expressing basket cells, making GABAergic synapses onto cell bodies and proximal dendrites of pyramidal cells, control pyramidal cell activity and participate in network
Tuncay Baubec et al.
Cell, 153(2), 480-492 (2013-04-16)
To gain insight into the cellular readout of DNA methylation, we established a strategy for systematically profiling the genome-wide distribution of chromatin-interacting factors. This enabled us to create genomic maps for the methyl-CpG-binding domain (MBD) family of proteins, including disease-relevant
Tim J Viney et al.
Nature neuroscience, 16(12), 1802-1811 (2013-10-22)
Hippocampal sharp waves are population discharges initiated by an unknown mechanism in pyramidal cell networks of CA3. Axo-axonic cells (AACs) regulate action potential generation through GABAergic synapses on the axon initial segment. We found that CA3 AACs in anesthetized rats

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