822856

TSKgel^® UltraSW Aggregate (3 µm) HPLC Columns

L x I.D. 30 cm × 7.8 mm, diol phase

• 別名: TSKgel^® Size Exclusion (SW-Type) HPLC Column
• UNSPSCコード: 41115711

特性

• product name: TSK-GEL^®サイズ排除(SWタイプ)HPLCカラム, phase diol, L × I.D. 30 cm × 7.8 mm, 3 μm particle size
• 物質: stainless steel
• 認証: suitable for USP L20; suitable for USP L59
• 製品種目: TSKgel^®
• メーカー／製品名: Tosoh UltraSW Aggregate, 22856
• パラメーター: ≤0.5 M salt concentration; 0-100% aqueous soluble organic solvents; 1 mL/min flow rate; 10-30 °C temperature; 120 bar max. pressure
• テクニック: HPLC: suitable
• L × 内径: 30 cm × 7.8 mm
• マトリックス: silica particle platform
• マトリックス活性基: diol phase
• 粒径: 3 μm
• ポアサイズ: 300 Å
• 使用pH: 2.5-7.5
• 分離法: size exclusion (SEC)

詳細

詳細

The TSKgel SuperSW and UltraSW mAb columns consist of three specialized columns designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best for aggregation, dimer, and fragmentation, making it the best method for heterogeneity studies.

TSKgel UltraSW Aggregate columns have a slightly larger pore size and smaller (3 μm) particle size than the industry-leading TSKgel G3000SWxl (5 μm) and SuperSW3000 (4 μm) columns. These 30 cm x 7.8 mm ID silica-based, stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates.

The calibration curve of the TSKgel UltraSW Aggregrate column shows a separation range up to around 2 million Da, which provides better resolution of aggregates/multimers of a mAb than the TSKgel SuperSW mAb columns..

物理的形状

Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.

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法的情報

TSKgel is a registered trademark of Tosoh Corporation