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product name
Discovery® C18 HPLCカラム, 5 μm particle size, L × I.D. 10 cm × 4.6 mm
物質
stainless steel column
品質水準
認証
suitable for USP L1
製品種目
Discovery®
特徴
endcapped
メーカー／製品名
Discovery®
包装
1 ea of
標識化の程度
12% Carbon loading
パラメーター
≤70 °C temp. range
400 bar pressure (5801 psi)
テクニック
HPLC: suitable
LC/MS: suitable
L × 内径
10 cm × 4.6 mm
表面積
300 m2/g
表面被覆率
3 μmol/m2
不純物
<10 ppm metals
マトリックス
silica gel, high purity, spherical particle platform
fully porous particle
マトリックス活性基
C18 (octadecyl) phase
粒径
5 μm
ポアサイズ
180 Å
operating pH range
2-8
アプリケーション
food and beverages
分離法
reversed phase
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詳細
C18カラムを指定するあらゆる方法でDiscovery®C18カラムを使用してください。優れたピーク形状、再現性、安定性により、難しいものからルーチンまであらゆるC18カラムを用いる方法で本品を選択していただけます。
アプリケーション
- Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase.: Utilizes the Discovery® C18 HPLC Column for developing a novel enzymatic assay, aiding in malaria research and potential therapeutic target exploration (Pedro et al., 2019).
特徴および利点
- 優れた再現性
- 塩基性、酸性分析対象物に対する優れたピ-ク形状
- 安定で、低ブリ-ドのLC-MS分離
- ペプチドや小さなタンパク質の分離
- 多くの同等のC18カラムよりも低い疎水性で迅速な分析を提供
法的情報
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
T Nagano et al.
Journal of dental research, 88(9), 823-828 (2009-09-22)
Mmp-20 and Klk4 are the two key enamel proteases. Can both enzymes process amelogenin to generate the major cleavage products that accumulate during the secretory stage of amelogenesis? We isolated Mmp-20 and Klk4 from developing pig teeth and used them
Yuan-Qing Xia et al.
Rapid communications in mass spectrometry : RCM, 20(12), 1831-1837 (2006-05-18)
A major challenge in selecting an appropriate stationary phase for diastereomeric separation is that it is difficult to predict which of the commercially available stationary phases could achieve the required liquid chromatographic (LC) separation. This work describes the selection and
T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Satoru Sonoke et al.
Cancer research, 68(21), 8843-8851 (2008-11-01)
The pharmacokinetics and antitumor activity of pegylated small interfering RNA (siRNA)/cationic liposome complexes were studied after systemic administration to mice. We designed pegylated-lipid carriers for achieving increased plasma concentrations of RNA and hence improved accumulation of RNA in tumors by
Yoshinori Masukawa et al.
Journal of lipid research, 49(7), 1466-1476 (2008-03-25)
Ceramides (CERs) in human stratum corneum (SC) play physicochemical roles in determining barrier and water-holding functions of the skin, and specific species might be closely related to the regulation of keratinization, together with other CER-related lipids. Structures of those diverse
関連コンテンツ
Discovery C18 and C8 HPLC Columns products offered
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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