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Merck

568502-U

Supelco

Discovery® HS C18 HPLCカラム

5 μm particle size, L × I.D. 15 cm × 2.1 mm

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About This Item

UNSPSCコード:
41115700
eCl@ss:
32110501
NACRES:
SB.52

物質

stainless steel column

品質水準

認証

suitable for USP L1

製品種目

Discovery®

特徴

endcapped

メーカー/製品名

Discovery®

包装

1 ea of

標識化の程度

20% Carbon loading

パラメーター

≤70 °C temp. range
400 bar pressure (5801 psi)

テクニック

HPLC: suitable
LC/MS: suitable

L × 内径

15 cm × 2.1 mm

表面積

300 m2/g

表面被覆率

3.2 μmol/m2

不純物

<10 ppm metals

マトリックス

silica gel, high purity, spherical particle platform
fully porous particle

マトリックス活性基

C18 (octadecyl) phase

粒径

5 μm

ポアサイズ

120 Å

operating pH range

2-8

アプリケーション

food and beverages

分離法

reversed phase

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特徴および利点

  • 安定で、低ブリ-ドのLC-MS分離
  • 分析から分取まで適応可能
  • 安定性が高く、操作間、ロット間の再現性を保証
  • 疎水性が高く、難しい分析対象物の高い分離能

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法的情報

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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試験成績書(COA)

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Abad Khan et al.
Talanta, 84(3), 789-801 (2011-04-13)
A new, simple, economical and validated high-performance liquid chromatography linked with electrochemical detector (HPLC-ECD) method has been developed and optimized for different experimental parameters to analyze the most common monothiols and disulfide (cystine, cysteine, homocysteine, methionine, reduced (GSH) and oxidized
Awantika Singh et al.
Rapid communications in mass spectrometry : RCM, 29(6), 485-496 (2015-07-15)
Adhatoda beddomei and Adhatoda vasica are popular Ayurvedic medicinal plants in India, belonging to the family Acanthaceae. Tricyclic quinazoline alkaloids are found to be the most abundant in these plants which are responsible for broad-spectrum medicinal properties. This study aims
Swati Jaiswal et al.
Journal of chromatographic science, 55(6), 617-624 (2017-03-24)
Tuberculosis (TB) with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome represents the most common infectious diseases worldwide. Anti-TB drugs are used concurrently with antiretroviral drug for treatment of TB-HIV co-morbidities. Due to lower risk of interaction with protease inhibitors, rifabutin is
Ismail Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1033-1034, 261-270 (2016-09-07)
A simple, economical, fast, and sensitive RP-HPLC-UV method has been developed for the simultaneous quantification of Sorafenib and paclitaxel in biological samples and formulations using piroxicam as an internal standard. The experimental conditions were optimized and method was validated according
Lucie Zelena et al.
Journal of pharmaceutical and biomedical analysis, 137, 70-77 (2017-01-17)
Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients. A simple, fast and sensitive high-performance liquid chromatography (HPLC) method was developed in order to determine efavirenz in three types of samples provided from pharmacokinetic studies. The analysis

資料

The field of proteomics is continually looking for new ways to investigate protein dynamics within complex biological samples. Recently, many researchers have begun to use RNA interference (RNAi) as a method of manipulating protein levels within their samples, but the ability to accurately determine these protein amounts remains a challenge. Fortunately, over the past decade, the field of proteomics has witnessed significant advances in the area of mass spectrometry. These advances, both in instrumentation and methodology, are providing researchers with sensitive assays for both identification and quantification of proteins within complex samples. This discussion will highlight some of these methodologies, namely the use of Multiple Reaction Monitoring (MRM) and Protein-AQUA.

関連コンテンツ

HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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