product name
Astec®CHIROBIOTIC®TAG Chiral HPLC Column（キラルHPLCカラム）, 5 μm particle size, L × I.D. 25 cm × 21.2 mm
物質
stainless steel column
認証
suitable for USP L63
詳細
HPLC column
製品種目
Astec®
包装
pkg of 1 ea
メーカー／製品名
Astec®
パラメーター
0-45 °C temperature
241 bar pressure (3500 psi)
テクニック
HPLC: suitable
LC/MS: suitable
L × 内径
25 cm × 21.2 mm
マトリックス
High-purity silica gel particle platform
fully porous particle
マトリックス活性基
teicoplanin aglycone phase
粒径
5 μm
ポアサイズ
100 Å
operating pH range
3.0-6.8
分離法
chiral
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詳細
3つの炭化水素基を除去したため、CHIROBIOTIC® TAGの相補的な選択性がCHIROBIOTIC® Tに与えられます。多くのアミノ酸α、β、γおよび環状、さらに特にイオウ含有メチオニン、ヒスチジン、およびシステインへの分割能が向上します。オキサゾリジノン、ヒダントイン、ジアゼピンなど、多くの中性分子が高い分割能を示し、とりわけメタノール、エタノール、アセトニトリルなどの単一溶媒で高くなります。一部の酸性分子も高い選択性を示します。
- 結合相:テイコプラニンアグリコン
- 動作するpH範囲:3.0～6.8
- 粒径:5、10、または16 μm
- 細孔径:100 Å
法的情報
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Choose from one of the most recent versions:
Ilaria D'Acquarica et al.
Journal of chromatography. A, 1061(2), 167-173 (2005-01-12)
We describe a new tandem-columns chiral-achiral HPLC arrangement by using a chiral column (CHIROBIOTIC TAG) connected in series with an achiral column (Spherisorb S5 SCX), based on a strong cationic exchange mechanism; this approach is very useful for the analysis
Abdulrahman A Al-Majed
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary
Markus Fuereder et al.
Journal of chromatography. A, 1236, 123-131 (2012-04-03)
Teicoplanin aglycone-based chromatography columns (Chirobiotic TAG) enable amino acid enantioseparation with aqueous mobile phases, which perfectly accommodates the distinct hydrophilicity of most amino acids. Therefore, this stationary phase constitutes a promising option in particular for preparative-scale separations that require high
Adsorption behavior of a teicoplanin aglycone bonded stationary phase under harsh overload conditions
Bechtold, Matthias, et al.
Journal of Chromatography A, 1154 (1-2), 2477-2286 (2007)
Matthias Bechtold et al.
Journal of chromatography. A, 1113(1-2), 167-176 (2006-02-28)
The suitability of a teicoplanin-aglycone based chiral stationary phase for the simulated moving bed (SMB) enantioseparation of amino acids under enzyme-compatible conditions was shown following a procedure that is based solely on model-based simulations and HPLC experiments. A set of
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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