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由来生物
mouse
品質水準
結合体
unconjugated
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
1.4C3, monoclonal
フォーム
buffered aqueous solution
分子量
antigen 110 kDa
交差性
human
濃度
~1 mg/mL
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2-4 μg/mL using human tonsil tissue
immunohistochemistry (frozen sections): 2-4 μg/mL using human tonsil tissue
western blot: suitable
アイソタイプ
IgG1
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... VCAM1(7412)
詳細
VCAM-1(Vascular Cell Adhesion Molecule-1) belongs to immunoglobulin-related gene superfamily of adhesion molecules and is a 110kD cell surface integral membrane glycoprotein. It is expressed mainly by cytokine-activated endothelium and plays a pivotal role in numerous immunological and inflammatory responses. Monoclonal anti-vascular cell adhesion molecule 1 antibody can be used in immunohistochemistry for formalin-fixed, paraffin-embedded tissue sections. Mouse anti-vascular cell adhesion molecule 1 antibody reacts specifically with human vascular cell adhesion molecule-1 (CD106 or INCAM-110).
免疫原
stimulated HUVEC cells and mouse NS1 cells.
アプリケーション
Monoclonal anti-vascular cell adhesion molecule 1 antibody can be used in immunoblotting and western blotting.
物理的形状
PBS溶液 (0.08%アジ化ナトリウム含有)。
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
V9263-100UG-PW:
V9263-VAR:
V9263-100UG:
V9263-BULK:
Kumiko Nishimura et al.
Life sciences, 203, 276-281 (2018-04-24)
Type 3 iodothyronine deiodinase (D3), which converts thyroxine (T4) and 3,5,3'-triiodothyronine (T3) to 3,3',5'-triiodothyronine (rT3) and 3,3'-diiodothyronine (T2), respectively, inactivates thyroid hormones. We investigated the expression and regulation of D3 in human cardiomyocytes which were differentiated from human induced pluripotent
Darren G Woodside et al.
Journal of immunology (Baltimore, Md. : 1950), 176(8), 5041-5049 (2006-04-06)
Cell adhesion mediated by the interaction between integrin alpha4beta1 and VCAM-1 is important in normal physiologic processes and in inflammatory and autoimmune disease. Numerous studies have mapped the alpha4beta1 binding sites in VCAM-1 that mediate cell adhesion; however, little is
A G Kumar et al.
Journal of immunology (Baltimore, Md. : 1950), 153(9), 4088-4098 (1994-11-01)
Vascular cell adhesion molecule-1 (VCAM-1) is a member of the Ig superfamily that shows increased expression in a number of pathologic conditions. The role of VCAM-1 in human disease remains undefined and murine models are being extensively studied to help
Chengjie Ma et al.
Molecular medicine reports, 22(1), 483-493 (2020-04-23)
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American journal of physiology. Heart and circulatory physiology, 307(10), H1419-H1429 (2014-09-23)
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ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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