由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
化学種の反応性
human, rat, mouse
テクニック
indirect immunofluorescence: 10 μg/mL using CV-1 cells
western blot: 2 μg/mL
UniProtアクセッション番号
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... VAMP4(8674)
mouse ... Vamp4(53330)
rat ... Vamp4(364033)
詳細
Vesicle associated membrane protein 4 (VAMP4) is localized on human chromosome 1q24-q25. It is expressed in the skeletal muscle and liver. The protein is part of the soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) family. VAMP4 is localized to the trans-Golgi network.
特異性
Anti-Vesicle Associated Membrane Protein 4 detectsVAMP-4.
免疫原
recombinant rat VAMP-4.
生物化学的／生理学的作用
Vesicle associated membrane protein 4 (VAMP4) mediates trans-Golgi network trafficking of membrane-bound and secreted proteins. Studies have shown that VAMP4 has a role in maintaining the structure of the Golgi apparatus.
物理的形状
PBS溶液(1.0mg/mL BSA, 0.05%アジ化ナトリウム含有)。
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
V4514-100UG:
V4514-BULK:
V4514-VAR:
V4514-100UG-PW:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Akiko Shitara et al.
Molecular biology of the cell, 30(3), 324-332 (2018-12-13)
Lumen establishment and maintenance are fundamental for tubular organs physiological functions. Most of the studies investigating the mechanisms regulating this process have been carried out in cell cultures or in smaller organisms, whereas little has been done in mammalian model
Vesicle-associated membrane protein 4, a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish
Mona MS et al
Molecular Genetics and Metabolism, 85(2), 133-139 null
VAMP4 is required to maintain the ribbon structure of the Golgi apparatus
Akiko S et al.
Molecular and Cellular Biochemistry (2013)
Vera Kreykenbohm et al.
European journal of cell biology, 81(5), 273-280 (2002-06-18)
Two mammalian proteins, vtila and vtilb, are homologous to the yeast Q-SNARE Vtilp which is part of several SNARE complexes in different transport steps. In vitro experiments suggest distinct functions for vtila and vtilb. Here we compared the subcellular localization
M Steegmaier et al.
Molecular biology of the cell, 10(6), 1957-1972 (1999-06-08)
The trans-Golgi network (TGN) plays a pivotal role in directing proteins in the secretory pathway to the appropriate cellular destination. VAMP4, a recently discovered member of the vesicle-associated membrane protein (VAMP) family of trafficking proteins, has been suggested to play
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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