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主要文書

安全性情報

適用法令

V0130

[Arg⁸]-Vasotocin acetate salt

Name: [Arg<SUP>8</SUP>]-Vasotocin acetate salt
Brand: SIGMA

≥97% (HPLC)

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About This Item

実験式（ヒル表記法）:

C₄₃H₆₇N₁₅O₁₂S₂

CAS番号:

74927-14-3

分子量:

1050.22

MDL番号:

MFCD00133923

UNSPSCコード:

51111800

PubChem Substance ID:

24900689

NACRES:

NA.32

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Slide 1 of 1

1 of 1

Sigma-Aldrich

R4658

PEPTITE-2000^®

品質水準

200

アッセイ

≥97% (HPLC)

溶解性

H₂O: soluble 20 mg/mL, clear, colorless

UniProtアクセッション番号

P01185

保管温度

−20°C

SMILES記法

CC[C@@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O

InChI

1S/C43H67N15O12S2/c1-3-21(2)34-41(69)53-26(12-13-31(45)60)37(65)55-28(17-32(46)61)38(66)56-29(20-72-71-19-24(44)35(63)54-27(39(67)57-34)16-22-8-10-23(59)11-9-22)42(70)58-15-5-7-30(58)40(68)52-25(6-4-14-50-43(48)49)36(64)51-18-33(47)62/h8-11,21,24-30,34,59H,3-7,12-20,44H2,1-2H3,(H2,45,60)(H2,46,61)(H2,47,62)(H,51,64)(H,52,68)(H,53,69)(H,54,63)(H,55,65)(H,56,66)(H,57,67)(H4,48,49,50)/t21-,24+,25+,26+,27+,28+,29+,30+,34+/m1/s1

InChI Key

OXDZADMCOWPSOC-QLWWDPKZSA-N

遺伝子情報

human ... AVP(551)

Amino Acid Sequence

Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]

アプリケーション

[Arg8]-Vasotocin acetate salt was used as a test compound for studying whether it can regulate the interspecific cooperative behaviour in fish. The product was used for inducing parturition in viviparous females to study reproduction in oviparous and viviparous lizard females of species Zootoca vivipara.

生物化学的／生理学的作用

[Arg8]-Vasotocin (AVT) is a neurohypophyseal peptide of the vasopressin/oxytocin hormone family that mediates social behaviors, coregulates the adrenocortical stress response as well as maintains water balance. AVT stimulates neurones in the mammalian central nervous system.

調製ノート

[Arg8]-Vasotocin acetate salt dissolves in water at 20 mg/ml to yield a clear, colorless solution.

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

V0130-5MG-PW:
V0130-1MG-PW:
V0130-VAR:
V0130-1MG:
V0130PROC:
V0130-BULK:
V0130-5MG:
V0130-PPG:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA）を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

An essential role of the arginine vasotocin system in mate-guarding behaviors in triadic relationships of medaka fish (Oryzias latipes).

Saori Yokoi et al.

PLoS genetics, 11(2), e1005009-e1005009 (2015-02-27)

To increase individual male fitness, males of various species remain near a (potential) mating partner and repel their rivals (mate-guarding). Mate-guarding is assumed to be mediated by two different types of motivation: sexual motivation toward the opposite sex and competitive

Mutational analysis and molecular modeling of the nonapeptide hormone binding domains of the [Arg8]vasotocin receptor.

H Hausmann et al.

Proceedings of the National Academy of Sciences of the United States of America, 93(14), 6907-6912 (1996-07-09)

To identify determinants that form nonapeptide hormone binding domains of the white sucker Catostomus commersoni [Arg8]vasotocin receptor, chimeric constructs encoding parts of the vasotocin receptor and parts of the isotocin receptor have been analyzed by [(3,5-3H)Tyr2, Arg8]vasotocin binding to membranes

Brain arginine vasotocin immunoreactivity differs between urban and desert curve-billed thrashers, Toxostoma curvirostre: relationships with territoriality and stress physiology.

H Bobby Fokidis et al.

Brain, behavior and evolution, 79(2), 84-97 (2011-11-10)

The neuropeptide arginine vasotocin (AVT: the avian homolog of vasopressin) has numerous functional roles including mediating social behaviors, coregulating the adrenocortical stress response and maintaining water balance. These functions of AVT make it susceptible to environmental influence, yet little is

Pharmacological characterization of arginine vasotocin vascular smooth muscle receptors in the trout (Oncorhynchus mykiss) in vitro.

D J Conklin et al.

General and comparative endocrinology, 114(1), 36-46 (1999-03-30)

Arginine vasotocin (AVT) is present in the neurohypophysis of all nonmammalian vertebrates and it appears to be the antecedent of the neurohypophysial nonapeptide hormones. Relatively little is known about AVT receptors in lower vertebrates, especially fish, and the present study

[Arg8]vasotocin excites neurones in the dorsal vagal complex in vitro: evidence for an action through novel class(es) of CNS receptors.

C D Ingram et al.

Journal of neuroendocrinology, 6(4), 415-422 (1994-08-01)

Using extracellular recordings from brainstem slices in vitro, it was demonstrated that a high proportion (38/56) of neurones in the dorsal vagal complex of dioestrus, virgin female rats exhibit an excitatory response to [Arg8]-vasotocin (AVT). Pharmacological characterization suggests that these

主要文書

安全性情報

[Arg⁸]-Vasotocin acetate salt

≥97% (HPLC)

About This Item

おすすめの製品

特性

品質水準

アッセイ

溶解性

UniProtアクセッション番号

保管温度

SMILES記法

InChI

InChI Key

遺伝子情報

詳細

Amino Acid Sequence

アプリケーション

生物化学的／生理学的作用

調製ノート

安全性情報

保管分類コード

WGK

引火点(°F)

引火点(℃)

個人用保護具 (PPE)

適用法令

Jan Code

資料

試験成績書（COA）

以前この製品を購入いただいたことがある場合

参考文献

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