由来生物
chicken
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
lyophilized powder
化学種の反応性
human
テクニック
neutralization: suitable
western blot: suitable
UniProtアクセッション番号
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TGFB1(7040)
関連するカテゴリー
詳細
Transforming Growth Factor-β1 (TGF β1) is a multifunctional protein that can stimulate or inhibit cellular proliferation. Mesenchymal origin cells are stimulated by TGF β1 while T and B lymphocytes, keratinocytes, hepatocytes and epithelial cells are inhibited by TGF β1. It facilitates in tissue growth and differentiation by participating in myogenesis, osteogenesis, adipogenesis, chondrogenesis, epithelial cell differentiation and immune cell function. Anti-Transforming Growth Factor-β1 antibody can be used in neutralization assay. Chicken anti-TGF β1 reacts specifically with recombinant human TGF-β1 or TGF-β1.2.
特異性
The antibody will neutralize the biological activity of recombinant human TGF-β1 and porcine TGF-β1.2.
免疫原
Recombinant human TGF-β1 expressed in CHO cells.
アプリケーション
Anti-Transforming Growth Factor-β1 antibody can be used in western blotting.
物理的形状
Lyophilized from 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
J H Kehrl et al.
The Journal of experimental medicine, 163(5), 1037-1050 (1986-05-01)
This study examines the potential role of transforming growth factor beta (TGF-beta) in the regulation of human T lymphocyte proliferation, and proposes that TGF-beta is an important autoregulatory lymphokine that limits T lymphocyte clonal expansion, and that TGF-beta production by
G D Shipley et al.
Cancer research, 46(4 Pt 2), 2068-2071 (1986-04-01)
Type beta transforming growth factor-growth inhibitor (TGF beta/GI) causes normal human prokeratinocytes to arrest growth predominantly in the G1 phase of the cell cycle within 48 h after log phase cultures are exposed to the factor in serum-free medium. The
S Cheifetz et al.
Cell, 48(3), 409-415 (1987-02-13)
A new homodimer form of transforming growth factor-beta (TGF-beta), TGF-beta 2, has been identified in porcine blood platelets. TGF-beta 2 is homologous to ordinary TGF-beta (TGF-beta 1), which is also present in platelets. TGF-beta 1.2, a heterodimer containing one TGF-beta
C B Childs et al.
Proceedings of the National Academy of Sciences of the United States of America, 79(17), 5312-5316 (1982-09-01)
High concentrations of fetal bovine serum induced colony formation in soft agar by anchorage-dependent, nontransformed mouse AKR-2B and rat NRK cells. The colony-stimulating activity in fetal bovine serum was precipitated by 45% saturated ammonium sulfate and migrated in molecular sieve
I Hayashi et al.
Journal of cellular physiology, 125(1), 82-90 (1985-10-01)
Primary monolayer cultures of adult rat hepatocytes can be induced to undergo DNA synthesis in serum-free medium in the presence of insulin, glucagon, and epidermal growth factor (three factors). We have found that hepatocyte DNA synthesis is affected not only
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