SRP8037

IL-36γ mouse

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized

• 別名: Interleukin-1 family member 9, Interleukin-36γ, SSI-3
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• product name: IL-36γ mouse, recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
• 由来生物: mouse
• リコンビナント: expressed in E. coli
• 結合体: untagged
• アッセイ: >95% (SDS-PAGE)
• 形状: lyophilized
• 分子量: ~17 kDa
• 包装: pkg of 10 μg
• 不純物: <0.01 EU/μg endotoxin, tested
• 色: white
• UniProtアクセッション番号: Q8R460
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... Il36g(215257)

詳細

詳細

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

物理的形状

Lyophilized from PBS and 0.5% trehalose.

再構成

Reconstitute with 100 μL deionized water.

その他情報

IL-36gamma (mouse) (aa 13-164) is untagged.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable