SRP4634

VEGF-C マウス由来

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 別名: VEGFC, 血管内皮増殖因子-C
• MDL番号: MFCD03458368
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: mouse
• リコンビナント: expressed in E. coli
• アッセイ: ≥90% (SDS-PAGE)
• フォーム: lyophilized
• 有効性: >200 ng/mL ED₅₀
• 分子量: ~18.0 kDa
• 包装: pkg of 10 μg
• 保管条件: avoid repeated freeze/thaw cycles
• 不純物: endotoxin, tested
• NCBIアクセッション番号: P97953
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... Vegfc(22341)

詳細

詳細

VEGF-C (vascular endothelial growth factor-C) is a member of the VEGF family of structurally related proteins. The gene encoding this protein is localized on mouse chromosome 8. The product here (VEGF-C from mouse) is a 129 amino acid recombinant protein that lacks the N-terminal and C-terminal extensions and contains only the middle third VEGF homology domain. Mouse VEGF-C exhibits about 85% homology with human and 97% homology with rat VEGF-C.

生物化学的／生理学的作用

VEGF-C (vascular endothelial growth factor-C) has a role in lymphangiogenesis. It functions via the VEGF receptor-3 (VEGFR-3). Studies have shown that lymphatic endothelial cells do not form sprouting capillaries without VEGF-C. It has also been observed that this protein stimulates tumor lymphangiogenesis in xenotransplanted and transgenic mouse models of cancer.

物理的形状

凍結乾燥品(酢酸溶液、VEGF-C 1 μgあたり50 μg BSA含有)。

再構成

バイアルは、開封前に遠心してください。凍結融解の繰り返しは避けてください。

Reconstitute in 0.1% acetic acid to a concentration of 0.1-1.0 mg/mL.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable