SRP3279

BMP-5 human

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

• 別名: none
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in CHO cells
• アッセイ: ≥95% (HPLC); ≥95% (SDS-PAGE)
• 形状: lyophilized
• 有効性: 0.5-1.0 μg/mL ED₅₀
• 分子量: 31.2 kDa
• 包装: pkg of 10 μg
• 不純物: <0.1 EU/μg endotoxin, tested
• 色: white to off-white
• UniProtアクセッション番号: P22003
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... BMP5(653)

詳細

詳細

As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs.

生物化学的／生理学的作用

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 15.6 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.

物理的形状

Lyophilized with no additives.

再構成

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable