SRP0705

IFNA4

recombinant

• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• リコンビナント: expressed in E. coli
• アッセイ: 70-95% (SDS-PAGE)
• フォーム: lyophilized powder
• 分子量: ~19.6 kDa
• アクセッション番号: P05014
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... IFNA4(3441)

詳細

生物化学的／生理学的作用

Recombinant Human IFNA4 was expressed in E. coli cells. All known subtypes of IFN- alpha show the same antiviral antiparasitic, antiproliferative activities. IFN-alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. IFN-alpha and IFN-beta are thought to bind to the same receptor. Signal transduction mechanisms elicited after binding of IFN-alpha to its receptors involves tyrosine phosphorylation (see also: PTK; protein tyrosine kinase) of various non-receptor tyrosine kinases belonging to the Janus kinases.

再構成

Formulated as a lyophilized protein from a 0.2 um filtered solution in Tris and NaCl, pH 8.0. Upon reconstitution, working aliquots can be stored at 2-8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.

保管および安定性

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable