SML3345

LSL 60101

≥98% (HPLC)

• 別名: 2-(1-Benzofuran-2-yl)-1H -imidazole, 2-(2-Benzofuranyl)-1H -imidazole (ACI), Garsevil, LSL60101
• 実験式（ヒル表記法）: C₁₁H₈N₂O
• CAS番号: 150985-54-9
• 分子量: 184.19
• MDL番号: MFCD17292409
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: [nH]1c(ncc1)c2[o]c3c(c2)cccc3
• InChI: 1S/C11H8N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-7H,(H,12,13)
• InChI Key: VBFQIUOSXHUWCT-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

LSL 60101 is an orally available, potent and selective I2 imidazoline receptor ligand that induces morphological/biochemical changes in astroglia and exhibits neuroprotective activity. LSL 60101 decreases neuroinflammation and reverses cognitive deficits and impaired social behavior in 5XFAD mice Alzheimer’s model.

Orally available, potent and selective I2 imidazoline receptor ligand that exhibits neuroprotective activity

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable