SML2533

Jedi1

≥98% (HPLC)

• 別名: 2-Methyl-5-phenyl-3-furancarboxylic acid, 2-Methyl-5-phenyl-3-furoic acid, 2-Methyl-5-phenylfuran-3-carboxylic acid, 5-Phenyl-2-methyl-3-furancarboxylic acid
• 実験式（ヒル表記法）: C₁₂H₁₀O₃
• CAS番号: 108124-17-0
• 分子量: 202.21
• UNSPSCコード: 12352302
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: [O-]C(=O)c1c([o]c(c1)c2ccccc2)C
• InChI: 1S/C12H10O3/c1-8-10(12(13)14)7-11(15-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14)/p-1
• InChI Key: VLMNACSEESRUAK-UHFFFAOYSA-M

詳細

生物化学的／生理学的作用

Jedi1 is an activator of the mechanosensitive Piezo1 channel that binds at a different place from Yoda1. It exhibits long-range allosteric gating, activating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.

Piezo1 channel activator

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable