SML2187

RL5a

≥98% (HPLC)

• 別名: N2-[2-(2-Furanyl)-4-quinolinyl]-N1,N1-dimethyl-1,2-ethanediamine
• 実験式（ヒル表記法）: C₁₇H₁₉N₃O
• CAS番号: 133671-66-6
• 分子量: 281.35
• MDL番号: MFCD00929354
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to very dark brown
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: N(CCNc1c2c(nc(c1)c3[o]ccc3)cccc2)(C)C
• InChI: 1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
• InChI Key: CRGKLHXVNVZAPA-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.

potent inhibitor of the replication licensing system.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3