SML1544

VPC-14228

≥98% (HPLC)

• 別名: 2-Morpholino-4-phenylthiazole, 4-(4-Phenyl-2-thiazolyl)-morpholine, 4-(4-Phenylthiazol-2-yl)morpholine
• 実験式（ヒル表記法）: C₁₃H₁₄N₂OS
• CAS番号: 19983-28-9
• 分子量: 246.33
• MDL番号: MFCD00628805
• UNSPSCコード: 51111800
• PubChem Substance ID: 329825954
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 20 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: C1(N2CCOCC2)=NC(C3=CC=CC=C3)=CS1
• InChI: 1S/C13H14N2OS/c1-2-4-11(5-3-1)12-10-17-13(14-12)15-6-8-16-9-7-15/h1-5,10H,6-9H2
• InChI Key: MRNNJVNMXOZEQC-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR) that binds to AR DNA-binding domain (AR DBD). Apparently VPC-14228 blocks the transcriptional activity of constitutively active AR splice variants.

VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR).

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H319
• 注意書き: P264 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 - P501
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable