SML1526

Eltoprazine hydrochloride

≥98% (HPLC)

• 別名: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
• 実験式（ヒル表記法）: C₁₂H₁₆N₂O₂ · HCl
• CAS番号: 98206-09-8
• 分子量: 256.73
• MDL番号: MFCD06245586
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825943

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: H₂O: 10 mg/mL, clear
• 保管温度: room temp
• SMILES記法: [H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1
• InChI: 1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H
• InChI Key: JFSOSUNPIXJCIX-UHFFFAOYSA-N

詳細

詳細

Eltoprazine, a serotonergic agent, possesses specific anti-aggressive (serenic) properties in various animal models without triggering sedation, motor disturbances, or muscle relaxation.

生物化学的／生理学的作用

Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301 - H315 - H319 - H335
• 注意書き: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable