SML1483

Ogerin negative control

≥98% (HPLC)

• 別名: 3-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol
• 実験式（ヒル表記法）: C₁₇H₁₇N₅O
• CAS番号: 1125453-08-8
• 分子量: 307.35
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825912
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 20 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: NC1=NC(C2=CC(CO)=CC=C2)=NC(NCC3=CC=CC=C3)=N1
• InChI: 1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)
• InChI Key: RVKAHYFWSKSSQQ-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.

おすすめ製品

The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable