SML1247

NAB2

≥98% (HPLC)

• 別名: N-(2-Chlorobenzyl)-1-(2,5-dimethylphenyl)-1H-benzo[d]imidazole-5-carboxamide
• 実験式（ヒル表記法）: C₂₃H₂₀ClN₃O
• CAS番号: 1504588-00-4
• 分子量: 389.88
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 5 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: Clc1c(cccc1)CNC(=O)c2cc3nc[n](c3cc2)c4c(ccc(c4)C)C
• InChI: 1S/C23H20ClN3O/c1-15-7-8-16(2)22(11-15)27-14-26-20-12-17(9-10-21(20)27)23(28)25-13-18-5-3-4-6-19(18)24/h3-12,14H,13H2,1-2H3,(H,25,28)
• InChI Key: CZSLEMCYYGEGKP-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

NAB2 is a cell permeable and selective modifier of α-synuclein toxicity diverse cell types and PD neurons. NAB2 restores Rsp5/Nedd4 E3 ligase-dependent endosomal and endoplasmic reticulum–to-Golgi vesicle trafficking.

NAB2 is a cell permeable and selective modifier of α-synuclein toxicity.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable