SML0972

ORM-10103

≥98% (HPLC)

• 別名: 2-[(3,4-Dihydro-2-phenyl-2H-1-benzopyran-6-yl)oxy]-5-nitro-pyridine
• 実験式（ヒル表記法）: C₂₀H₁₆N₂O₄
• CAS番号: 488847-28-5
• 分子量: 348.35
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to light brown
• 溶解性: DMSO: 20 mg/mL, clear
• 保管温度: room temp
• SMILES記法: [N+](=O)([O-])c1cnc(cc1)Oc2cc3c(cc2)OC(CC3)c4ccccc4
• InChI: 1S/C20H16N2O4/c23-22(24)16-7-11-20(21-13-16)25-17-8-10-19-15(12-17)6-9-18(26-19)14-4-2-1-3-5-14/h1-5,7-8,10-13,18H,6,9H2
• InChI Key: GZONLGPIHCCJOI-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

ORM-10103 is a potent, specific inhibitor of the Na(+)/Ca(2+) exchanger, NCX.

ORM-10103 is a potent, specific inhibitor of the Na(+)/Ca(2+) exchanger, NCX. The compound ORM-10103 inhibits both inward and outward NCX currents with IC₅₀ values of 780 nM, and 960 nM, respectively. ORM-10103 blocks induced arrhythmias in canine cardiac tissue.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301,H413
• 注意書き: P264 - P270 - P273 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral - Aquatic Chronic 4
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable