SML0634

CID2858522

≥98% (HPLC)

• 別名: 1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]-ethanone
• 実験式（ヒル表記法）: C₂₈H₃₉N₃O₃
• CAS番号: 758679-97-9
• 分子量: 465.63
• MDL番号: MFCD20755108
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825572
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: Cc1cc2nc(NCCCO)n(CC(=O)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C)c2cc1C
• InChI: 1S/C28H39N3O3/c1-17-12-22-23(13-18(17)2)31(26(30-22)29-10-9-11-32)16-24(33)19-14-20(27(3,4)5)25(34)21(15-19)28(6,7)8/h12-15,32,34H,9-11,16H2,1-8H3,(H,29,30)
• InChI Key: CYCGGKILBWERDJ-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

CID2858522 specifically inhibits NF-kB activation downstream of protein kinsase C (PKC).

CID2858522 specifically inhibits NF-kB activation downstream of protein kinsase C (PKC). CID2858522 dose dependently inhibits NF-kB reporter activity in PMA-ionomycin stimulated HEK293 cells, but does not affect NF-kB activity in cells challenged with TNFa, retinoic acid, or stimulation of the toll-like receptor signaling pathway.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3