SBR00094

バルネムリン 塩酸塩

≥96% (HPLC), powder

• 別名: Econor
• 実験式（ヒル表記法）: C₃₁H₅₂N₂O₅S · HCl
• CAS番号: 133868-46-9
• 分子量: 601.28
• MDL番号: MFCD08458958
• UNSPSCコード: 51101500

特性

• 品質水準: 100
• アッセイ: ≥96% (HPLC)
• フォーム: powder
• 抗生物質活性スペクトル: Gram-negative bacteria; Gram-positive bacteria
• 作用機序: protein synthesis | inhibits
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: CC(C)[C@@H](N)C(NCC(C)(C)SCC(O[C@H]1[C@](C)([C@@H]2C)[C@@]3([H])[C@@](CC2)(CCC3=O)[C@@H](C)[C@H](O)[C@](C)(C=C)C1)=O)=O.Cl
• InChI: 1S/C31H52N2O5S.ClH/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31;/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37);1H/t19-,20+,22-,24-,25+,26+,29-,30+,31+;/m1./s1
• InChI Key: MFBPRQKHDIVLOJ-AFFLPQGKSA-N

詳細

詳細

Valnemulin Hydrochloride is an antibiotic which belongs to the class of compounds known as pleuromutilins. It is a semisynthetic derivative of the naturally occurring antibiotic tiamulin. Valnemulin Hydrochloride has activity against various Gram-positive and some Gram-negative bacteria, including Mycoplasma and some anaerobic bacteria, as well as the protozoan parasite Eimeria.

生物化学的／生理学的作用

Valnemulin Hydrochloride inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. More specifically, it binds to the peptidyl transferase center of the ribosome and interferes with the transfer of amino acids to growing polypeptide chains, leading to the inhibition of protein synthesis and bacterial death.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable