SBR00065

Rifampicin Ready Made Solution

50 mg/mL in DMSO

• 実験式（ヒル表記法）: C₄₃H₅₈N₄O₁₂
• CAS番号: 13292-46-1
• 分子量: 822.94
• UNSPSCコード: 41116107
• NACRES: NA.76

特性

• 形状: liquid
• 品質水準: 200
• 比活性: Antibacterial
• 濃度: 50 mg/mL in DMSO
• 抗生物質活性スペクトル: Gram-negative bacteria; Gram-positive bacteria; mycobacteria; viruses
• 作用機序: protein synthesis | interferes
• 保管温度: −20°C
• InChI: 1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
• InChI Key: JQXXHWHPUNPDRT-WLSIYKJHSA-N

詳細

詳細

Rifampicin is a microlide antibiotic effective against gram-positive and gram-negative bacteria, mycobacteria and viruses.

アプリケーション

• Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections.
• Rifampicin is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, and primary biliary cirrhosis (PBC).
• Rifampicin was also found active by inhibiting Tau Oligomer Propagation in Alzheimer’s disease.
• Rifampicin is used as a selection agent for agrobacterium mediated plant transformation.

生物化学的／生理学的作用

Inhibits the assembly of DNA and protein into mature virus particles.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.

その他情報

The product is supplied in DMSO at a concentration of 50 mg/mL. Working concentrations for agrobacterium selection are typically 10-50 mg/L.

安全性情報

• 危険有害性情報: H362
• 注意書き: P201 - P202 - P263 - P264 - P270 - P308 + P313
• 危険有害性の分類: Lact.
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): 188.6 °F - closed cup
• 引火点(℃): 87 °C - closed cup