SAB5702784

Anti-GABARAPL2 Antibody, clone 8Z8M8, Rabbit Monoclonal

• 別名: ATG8, ATG8C, GATE-16, GATE16, GEF-2, GEF2
• UNSPSCコード: 12352203
• NACRES: NA.46
• クローン: 8Z8M8, monoclonal
• application: WB
• 化学種の反応性: human, rat, rat
• テクニック: western blot: 1:500 - 1:2000

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 8Z8M8, monoclonal
• フォーム: liquid
• 分子量: 16 kDa
• 化学種の反応性: human, rat, rat
• 濃度: 0.3 mg/mL
• テクニック: western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: GSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
• UniProtアクセッション番号: P60520
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... GABARAPL2(11345)

詳細

詳細

Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 38-117 of human GABARAPL2 (P60520).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1