SAB5702746

Anti-ILF2 Antibody, clone 5P1K2, Rabbit Monoclonal

• 別名: NF45, PRO3063
• UNSPSCコード: 12352203
• NACRES: NA.46
• クローン: 5P1K2, monoclonal
• application: IHC; WB
• 化学種の反応性: human, rat, rat
• テクニック: immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 5P1K2, monoclonal
• フォーム: liquid
• 分子量: 43 kDa
• 化学種の反応性: human, rat, rat
• 濃度: 0.80 mg/mL
• テクニック: immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: SALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHT
• UniProtアクセッション番号: Q12905
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ILF2(3608)

詳細

詳細

The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ILF2 (Q12905).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB, IHC

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1