SAB5702705

Anti-SF3B1 Antibody, clone 4A3G9, Rabbit Monoclonal

• 別名: Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155
• UNSPSCコード: 12352203
• NACRES: NA.46
• クローン: 4A3G9, monoclonal
• application: IF; IHC; WB
• 化学種の反応性: rat, rat, human
• テクニック: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 4A3G9, monoclonal
• フォーム: liquid
• 分子量: 146 kDa
• 化学種の反応性: rat, rat, human
• 濃度: 0.27 mg/mL
• テクニック: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQ
• UniProtアクセッション番号: O75533
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SF3B1(23451)

詳細

詳細

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SF3B1 (O75533).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB, IHC, IF/ICC

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1