SAB5702178

Anti-Thyroid Peroxidase Antibody, clone 3C4A4, Rabbit Monoclonal

• 別名: MSA, TDH2A, TPX
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 3C4A4, monoclonal
• 形状: liquid
• 化学種の反応性: rat, human, rat
• 濃度: 1.09 mg/mL
• テクニック: immunohistochemistry: 1:50 - 1:200
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQA
• UniProtアクセッション番号: P07202
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TPO(7173)

詳細

詳細

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thyroid Peroxidase (P07202).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

IHC

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1