SAB5702066

Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal

• 別名: BCC7,LFS1,P53,TRP53,p53,TP53,BMFS5
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 7Z8X9, monoclonal
• フォーム: liquid
• 分子量: 53 kDa
• 交差性: mouse, mouse
• 濃度: 0.90 mg/mL
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: HKKLM
• UniProtアクセッション番号: P04637
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TP53(7157)

詳細

詳細

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

免疫原

A synthetic acetylated peptide around K382 of human p53 (NP_000537.3).

PBS with 0.05% proclin300,50% glycerol,pH7.3.

アプリケーション

DB, WB

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H317,H411
• 注意書き: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危険有害性の分類: Aquatic Chronic 2 - Skin Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3