SAB5702005

Anti-Bak Antibody, clone 7Q3T8, Rabbit Monoclonal

• 別名: BAK1,BAK,BAK-LIKE,BCL2L7
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 7Q3T8, monoclonal
• フォーム: liquid
• 分子量: 25 kDa
• 交差性: mouse, mouse
• 濃度: 0.089 mg/mL
• テクニック: immunohistochemistry: 1:50 - 1:100; western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: RQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIG
• UniProtアクセッション番号: Q16611
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... BAK1(578)

詳細

詳細

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

免疫原

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Recombinant fusion protein containing a sequence corresponding to amino acids 11-82 of human Bak (NP_001179.1).

アプリケーション

WB, IHC

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H317,H411
• 注意書き: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危険有害性の分類: Aquatic Chronic 2 - Skin Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3