SAB5701750

Anti-Phospho-CFL1-S3 antibody produced in rabbit

• UNSPSCコード: 12352203

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: liquid
• 化学種の反応性: mouse, human, rat
• 濃度: 0.71 mg/mL
• テクニック: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProtアクセッション番号: P23528
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer3)
• 遺伝子情報: human ... CFL1(1072)

詳細

詳細

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

免疫原

A phospho specific peptide corresponding to residues surrounding S3 of human CFL1

物理的形状

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable